作为结直肠癌的预测剂的ABO和Rhesus血型标记:一项前性观察性研究
Gowhar Rashid1,2, Gulzar A Bhat3, Tahseen Bilal Rather1
1Department of Clinical Biochemistry, SKIMS, Srinagar, India.
Medicine
|November 28, 2023
概括
这项研究发现,ABO/Rh血型与结直肠癌 (CRC) 风险或存活率之间没有联系. 血液型B和Rh阳性是最常见的,但没有影响这项研究中的患者结果.
科学领域:
- 在瘤学瘤学.
- 遗传学 是一个遗传学.
- 流行病学 流行病学
背景情况:
- ABO和Rhesus (Rh) 血型被研究用于癌症风险,但它们在结肠直肠癌 (CRC) 中的作用尚不清楚.
- 现有的研究表明,关于血液型作为不同癌症的预后因素的结果各不相同.
研究的目的:
- 调查 ABO 和 Rh 血型与结直肠癌 (CRC) 风险之间的关联.
- 探索这些血型对CRC患者存活率的潜在影响.
主要方法:
- 一项从2019年3月到2022年3月在印度斯里纳加的谢尔-伊-克什米尔医学科学研究所进行的前性观察性研究.
- 招募了246名被诊断患有结直肠癌 (CRC) 的患者.
- 分析了血型之间的关联,临床病理特征和3年生存率.
主要成果:
- 血型B (33.74%) 和Rh阳性 (91.87%) 在CRC患者中最为普遍.
- 在ABO/Rh血型和CRC风险或3年生存率之间没有发现显著的关联.
- 晚期癌症阶段和淋巴血管侵入与CRC风险增加有关 (P < .05).
结论:
- ABO和Rh血型似乎与结直肠癌 (CRC) 风险或生存率无关.
- 需要进一步的研究来澄清血型和CRC预后之间的确切关系.
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