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Updated: Jul 9, 2025

Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo
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Published on: September 18, 2014

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小细胞质dDNA和自之间的通信抑制了CGAS (循环GMP-AMP合成酶) 激活

Yu-Wei Luo1, Hongyu Ji1, Ai-Long Huang1

  • 1Key Laboratory of Molecular Biology on Infectious Disease, Ministry of Education, Chongqing Medical University, Chongqing, P.R. China.

Autophagy
|November 28, 2023
PubMed
概括

小细胞核DNA (scDNA) 抑制循环GMP-AMP合成酶 (CGAS) -STING1通路,通过阻断激活并通过自促成STING1降解. 这就产生了一个反循环,抑制了对较长DNA片段的先天免疫反应.

关键词:
造成的DNA损伤是DNA损伤.这就是PIK3C3C3的意思.一个刺1 一个刺1干扰子-β的干扰.小细胞质双链DNA小细胞质双链DNA

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