在患有持续的姿势感知头的患者中,静脉感知的表征
Megan J Kobel1, Andrew R Wagner1, John G Oas2
1Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus.
概括
持久的姿势感知性头 (PPPD) 患者对特定的自我运动线索的感知受损,特别是那些依赖于重力的线索. 这种前体缺陷受到同时出现的前体偏头痛 (VM) 的存在的影响.
科学领域:
- 神经科学是一个神经科学.
- 垂体系统研究研究 垂体系统研究
- 临床头 疾病 临床头
背景情况:
- 持续的姿势感知性头 (PPPD) 是一种慢性疾病,影响平衡和空间定向.
- 垂体感知,自我运动的感觉,对于保持稳定至关重要.
- 了解PPPD的特定感官处理缺陷是开发向治疗的关键.
研究的目的:
- 评价被诊断为PPPD的个体的被动自我运动感知.
- 在PPPD患者中识别特定的前庭感知缺陷.
- 探索同时发生的前庭偏头痛 (VM) 对这些缺陷的影响.
主要方法:
- 一项受病例控制的横截面研究,涉及13名PPPD患者和13名健康对照.
- 使用前庭门测试电池评估耳骨,半圆通道和通道-耳骨结合.
- 对各种被动运动刺激 (转移和倾斜) 的测量方向识别值.
主要成果:
- 与对照组相比,PPPD患者的上下z轴转换值显著更高.
- 患有PPPD和同时出现VM的患者显示z-翻译值升高.
- 患有PPPD但没有VM的患者表现出更高的滚动倾斜值.
结论:
- PPPD与被动自动运动感知中的普遍缺陷没有关联.
- 在PPPD中存在特定的前庭感知障碍,特别是在依赖于重力的任务 (z转换,滚动倾斜) 中.
- VM的同时出现改变了PPPD前庭感知缺陷的模式,表明严重感知暗示处理受损.
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