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κ-阿片类受体激活通过通过NF-κB通路调节巨细胞极化来减轻骨关节炎综合炎

Yi Shi1, Huaqiang Tao2, Xueyan Li1

  • 1Anesthesiology Department, Suzhou Municipal Hospital (North District), Nanjing Medical University Affiliated Suzhou Hospital, Suzhou 215000, China.

Acta biochimica et biophysica Sinica
|November 28, 2023
PubMed
概括

向卡帕-阿片类受体 (KOR) 可能治疗关节炎 (OA). 激活KOR可通过抑制巨细胞M1表型和OA患者和小鼠的NF-κB通路来减少炎症和膝盖疼痛.

关键词:
在 NF-κBB 中.巨细胞的两极分化骨关节炎是一种关节炎.突膜炎症是指突膜炎的炎症.κ-阿片类受体的受体

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