尾骨肌肉质量与内脏脂肪面积比率预测肝脏疾病
Eugene Han1, Yong-Ho Lee2,3, Sang Hoon Ahn2,4
1Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
Gut and liver
|November 28, 2023
概括
低肌肉质量与内脏肥胖相结合,显著增加了非酒精性脂肪性肝病 (NAFLD),肝纤维化和心血管疾病的风险. 这种组合对这些疾病的风险最高.
科学领域:
- 代谢健康 代谢健康
- 老年医学 老年医学
- 肝病学 肝病学是一种肝病学.
背景情况:
- 麻性内脏肥胖与非酒精性脂肪肝 (NAFLD) 相关疾病的联系尚未得到充分研究.
- 调查萨科佩尼亚和内脏肥胖对肝脏和冠状动脉并发症的综合影响至关重要.
研究的目的:
- 为了检查sarcopenia和内脏肥胖之间的关联.
- 确定这种关联对肝脏和冠状动脉并发症的影响.
主要方法:
- 尾骨肌量与内脏脂肪面积比率 (SV比率) 通过生物电阻分析进行评估.
- 使用过渡性弹性素学诊断的NAFLD和显著的肝纤维化.
- 高动脉样硬化心血管疾病 (ASCVD) 风险定义为10年ASCVD风险评分>10%.
主要成果:
- 最低SV比率的个体显示NAFLD风险增加,肝纤维化显著,ASCVD风险高.
- 最低的SV比率和肉症的组合产生了NAFLD (OR=3.11),显著的肝纤维化 (OR=2.03) 和高ASCVD风险 (OR=4.15) 的最高几率.
结论:
- 低的SV比率加上copenia显著提高了NAFLD的风险,显著的肝纤维化和高ASCVD风险.
- 这种结合的情况在已经有NAFLD高风险的个体中尤其有害.
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