肝与的比率是预测COVID-19患者氧气需求的风险因素
Hiromasa Nakayasu1, Shogo Sakurai1, Shuichi Sugiyama1
1Department of Respiratory Medicine, Shizuoka General Hospital, 4-27-1 Kita-Ando, Aoi, 420-0805 Shizuoka, Japan.
Infectious medicine
|November 28, 2023
概括
在COVID-19患者中,对氧气需求的关键预测因素包括肝与的比率,淋巴细胞数量,D-二次数和腹周. 这些因素有助于COVID-19患者的入院决定.
科学领域:
- 医学研究 医学研究
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- COVID-19带来了严重的呼吸困扰风险,需要氧气支持.
- 识别氧气需求的早期预测因素对于患者管理至关重要.
- 这项研究调查了COVID-19患者与氧气需求相关的风险因素.
研究的目的:
- 确定临床,实验室和放射学因素,预测在住院COVID-19患者中需要氧气治疗的需要.
- 用多变量后勤回归来确定氧气需求的独立风险因素.
- 在COVID-19大流行期间为临床决策和患者分拣提供信息.
主要方法:
- 在2020年8月至2021年8月期间入院的170名COVID-19患者的回顾性分析.
- 在有氧需求和没有氧气需求的患者之间比较临床特征,实验室结果和放射学发现.
- 多变量后勤回归以确定氧气需求的独立预测因素.
主要成果:
- 需要氧气支持的患者年龄较大,体重指数较高,并患有更多的并发症.
- 较低的淋巴细胞计数,白蛋白和肝与的比率 (L/S) 与增加的氧气需求有关.
- 还观察到D-二聚体,肝酶,乳酸脱酶,氨酸-T,C反应蛋白,KL-6的升高,腹周/内脏脂肪的增加.
- 多变量分析确定了L / S,淋巴细胞计数,D-二次体和腹周为氧气需求的独立预测指标.
结论:
- 肝脏与脏的比率,淋巴细胞数量,D-二次数和腹周是COVID-19患者入院时氧气需求的重要预测指标.
- 这些发现可以帮助医疗保健专业人员在早期选和管理COVID-19患者.
- 利用这些预测因素可以优化医院资源分配和患者护理途径.
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