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Updated: Jul 9, 2025

Extracellular Protein Microarray Technology for High Throughput Detection of Low Affinity Receptor-Ligand Interactions
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Extracellular Protein Microarray Technology for High Throughput Detection of Low Affinity Receptor-Ligand Interactions

Published on: January 7, 2019

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近距离蛋白质组分析揭示了人类微质的ER-线粒体接口中的新型TREM2相互作用体

Chulhwan Kwak, Gina M Finan, Yu Rim Park

    bioRxiv : the preprint server for biology
    |November 28, 2023
    PubMed
    概括

    在骨髓细胞2 (TREM2) 上表达的触发受体在阿尔茨海默病 (AD) 中至关重要. 新的研究表明TREM2与线粒体-ER接触点的蛋白质相互作用,影响微质功能和AD病理学.

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    Study of Endoplasmic Reticulum and Mitochondria Interactions by In Situ Proximity Ligation Assay in Fixed Cells

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