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在活体体中,表型血管功能障碍扩展到大动脉之外,在Fibrillin-1 (FBN1) 突变的小鼠模型中

T Curry, M E Barrameda, T Currier Thomas

    bioRxiv : the preprint server for biology
    |November 28, 2023
    PubMed
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    由FBN1突变引起的马凡综合征 (MFS) 加快了血管衰老,特别是在男性中. 这项研究揭示了中央和大脑动脉的性别依赖性变化,模仿了MFS小鼠的自然衰老.

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