抗体对 SARS-CoV-2 Omicron 变种病毒的症状感染的反应,2021 年 12 月至 2022 年 6 月
Ryan Sandford1,2,3, Ruchi Yadav1, Emma K Noble1,2
1Centers for Disease Control and Prevention, Atlanta, GA, USA.
medRxiv : the preprint server for health sciences
|November 28, 2023
概括
对SARS-CoV-2 (严重急性呼吸系统综合征冠状病毒2) 感染的幽默免疫反应显示免疫球蛋白G (IgG) 抗体水平显著增加. 抗核体 (N) 和抗受体结合域 (RBD) 抗体都从急性疾病到康复期间大幅上升.
科学领域:
- 免疫学 免疫学 免疫学
- 病毒学 病毒学
- 传染性疾病 传染性疾病
背景情况:
- 症状性SARS-CoV-2感染引发幽默性免疫反应,其特征是产生抗体.
- 了解针对不同SARS-CoV-2蛋白质的免疫球蛋白G (IgG) 抗体水平的动态对于评估免疫力至关重要.
结论:
- 症状性SARS-CoV-2感染导致特定IgG抗体水平的强增加.
- 抗体增加的大小在核体和受体结合域目标之间有所不同.
- 通过IgG抗体测量的人口免疫力,在Omicron感染后的康复阶段显著增强.
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