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Updated: Jul 9, 2025

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
09:51

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

Published on: May 25, 2018

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通过提供稳定的CRISPR-Cas9 RNP的脂质纳米粒子来编辑肺和肝脏

Kai Chen, Hesong Han, Sheng Zhao

    bioRxiv : the preprint server for biology
    |November 28, 2023
    PubMed
    概括

    工程热稳定Cas9 (iGeoCas9) 在脂质纳米粒子 (LNP) 输送系统中显著提高了CRISPR基因组编辑效率. 这一突破使得器官中的精确的体内基因编辑能够提高安全性和可制造性.

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    Electroporation-Mediated Delivery of Cas9 Ribonucleoproteins and mRNA into Freshly Isolated Primary Mouse Hepatocytes

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    CRISPR/Cas9 Ribonucleoprotein-mediated Precise Gene Editing by Tube Electroporation08:31

    CRISPR/Cas9 Ribonucleoprotein-mediated Precise Gene Editing by Tube Electroporation

    Published on: June 20, 2019

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    相关概念视频

    CRISPR01:59

    CRISPR

    Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
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