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Updated: Jun 14, 2026

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COL:一个管道用于识别假定功能性的回合拼接

Zheng Li, Bandhan Sarker, Fengyu Zhao

    bioRxiv : the preprint server for biology
    |November 28, 2023
    PubMed
    概括

    识别功能性循环RNA (circRNAs) 是一个挑战. 一个新的计算管道,COL,有效地预测功能性circRNAs使用保存的拼接动机和高的反拼接率从单个样本.

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    RNA Splicing01:32

    RNA Splicing

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    Alternative RNA splicing is the regulated splicing of exons and introns to produce different mature mRNAs from a single pre-mRNA. Unlike in constitutive splicing where a single gene produces a single type of mRNA, alternative splicing allows an organism to produce multiple proteins from a single gene and plays an important role in protein diversity.
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    Alternative RNA splicing is the regulated splicing of exons and introns to produce different mature mRNAs from a single pre-mRNA. Unlike in constitutive splicing where a single gene produces a single type of mRNA, alternative splicing allows an organism to produce multiple proteins from a single gene and plays an important role in protein diversity.
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