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Updated: Jul 9, 2025

Production of Disulfide-stabilized Transmembrane Peptide Complexes for Structural Studies
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Production of Disulfide-stabilized Transmembrane Peptide Complexes for Structural Studies

Published on: March 6, 2013

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对于分泌成分与二次性免疫球蛋白A相互作用的结构和生化要求

Sonya Kumar Bharathkar1,2,3, Beth M Stadtmueller1,2,3

  • 1Department of Biochemistry, University of Illinois Urbana-Champaign, Urbana, Illinois 61801 USA.

bioRxiv : the preprint server for biology
|November 28, 2023
PubMed
概括

分泌性免疫球蛋白A (SIgA) 对于粘膜免疫至关重要. 这项研究确定了分泌成分 (SC) 中的关键残留物,这些残留物与二维IgA (dIgA) 结合,揭示了SIgA运输和功能的机制.

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Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library

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Antibody Structure01:10

Antibody Structure

Overview
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Antibodies consist of four polypeptide chains: two identical heavy...
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Antibody Structure and Classes

Antibodies, also known as immunoglobulins, are produced by B cells in response to foreign substances, such as bacteria and viruses. These proteins are critical for recognizing and neutralizing these substances, protecting the body from potential harm.
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Overview of Secretory Vesicles

Secretory vesicles, also known as dense core vesicles (DCVs), are membrane-bound vesicles that transport secretory proteins, such as hormones or neurotransmitters. Regulated secretory vesicles transport proteins from the trans-Golgi network to the exterior of the cell. Proteins present in regulated secretory vesicles are required to be rapidly exocytosed in large amounts upon a specific stimulus.
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Immunoglobulin-like Cell Adhesion Molecules

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Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
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Structure of Cadherins

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