梅奥的规范性研究:基于回归的规范性数据,针对30-91岁的年龄段,重点是波士顿命名测试,Trail Making测试和类别流利性
Aimee J Karstens1, Teresa J Christianson2, Emily S Lundt2
1Division of Neurocognitive Disorders, Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.
Journal of the International Neuropsychological Society : JINS
|November 28, 2023
概括
来自梅奥规范研究 (MNS) 的更新的神经心理学规范改善了对认知测试表现的解释. 这些来自梅奥诊所衰老研究 (MCSA) 的新规范,解释了认知不受损的成年人的年龄,性别和教育.
科学领域:
- 神经心理学 神经心理学
- 老年学是一门学科.
- 生物统计学 生物统计学
背景情况:
- 对神经心理测试表现的准确解释依赖于根据人口因素调整的规范性数据.
- 现有的规范性数据可能无法完全捕捉到老年人群对认知功能的复杂人口影响.
- 梅奥诊所关于衰老的研究 (MCSA) 提供了一个强大的数据集,用于制定更新的规范标准.
研究的目的:
- 利用梅奥规范研究 (MNS) 的数据,为神经心理测量制定更新的基于回归的规范数据.
- 为了检查年龄,性别和教育对基于人口的样本中神经心理测试表现的影响.
- 为了验证新开发的MNS规范与现有的标准,如梅奥的老年美国人规范研究 (MOANS).
主要方法:
- 分析了4428名30岁及以上的认知正常成年人参与MCSA的数据.
- 采用多变量线性回归来确定人口统计学 (年龄,年龄平方,性别,教育) 对测试成绩的影响.
- 开发了基于回归的规范公式,并将低得分 (T < 40) 的基准率与验证样本中的MOANS进行了比较.
主要成果:
- 人口因素,包括年龄 (解释6-27%的差异),性别 (0-13%),和教育 (2-10%),在神经心理学的测量中显示出可变的线性和二次效应.
- 在老年人验证样本中,MNS规范证明了识别低绩效的基础率的改善.
- 与MOANS相比,在基准率的整体和性别特异性模式中都观察到改善.
结论:
- 更新的规范性数据对于准确解释神经心理测试结果至关重要,考虑到复杂的人口学关联.
- 从规范样本中排除轻度认知障碍的个体对于保持准确性至关重要.
- 该MNS提供了一个宝贵的资源,用于当代神经心理评估老龄化个体.
关键词:
认知老龄化 认知老龄化动物流动性动物流动性基准利率是指基本的利率.执行职能 执行职能是指执行职能.轻度的认知障碍 轻度的认知障碍神经心理测试 神经心理测试神经心理学神经心理学心理测量是指心理测量.更多相关视频
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