肝硬度作为心脏病风险评估的基石
Joost Boeckmans1,2, Laurent Sandrin3, Christian Knackstedt4,5
1Metabolic Liver Research Center, I. Department of Medicine, University Medical Center Mainz, Mainz, Germany.
概括
肝硬度增加,这是代谢功能障碍相关的脂肪性肝病 (MASLD) 的标志物,与心脏病有关. 测量肝硬度可以帮助确定需要心脏评估的患者.
科学领域:
- 心脏病学 心脏病学
- 肝病学 肝病学是一种肝病学.
- 内部医学 内部医学
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 通常会进展为肝纤维化,增加肝硬度.
- 心血管疾病是MASLD患者中普遍存在的并发症,发病率正在上升.
- 新出现的证据将有或没有MASLD的肝硬与各种心脏疾病联系在一起.
研究的目的:
- 审查肝硬度在预测常见心血管疾病中的作用.
- 探索肝硬与心力衰竭,心律失常,冠心病和大动脉硬化之间的关联.
主要方法:
- 一个叙事审查研究论文发表到2023年9月.
- 在PubMed和Web of Science中使用关键词进行的搜索:"肝硬"",肝纤维化"和特定的心脏疾病.
- 分析的重点是使用振动控制的短暂弹性学和生物标志物面板进行肝纤维化评估的研究.
主要成果:
- 肝硬度增加与心力衰竭,心房动和冠心病相关.
- 在MASLD患者中肝硬度升高表明潜在的心脏问题.
- 肝硬度测量是MASLD心血管风险分层的一个有价值的工具.
结论:
- 增加的肝硬度是有代谢损害的患者心脏工作的指标.
- 对于肝硬度升高的患者,建议考虑心脏评估,包括生物标志物测试和成像.
- 肝硬度测量可以整合到MASLD患者的心脏病病例发现策略中.
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