与COVID-19相关的长期神经功能障碍:从流感和炎症性疾病中吸取教训?
Parker Volk1, Mohammadreza Rahmani Manesh1, Mary E Warren1
1Division of Medical Sciences, University of Victoria, Victoria, British Columbia, Canada.
Journal of neurochemistry
|November 28, 2023
概括
长期COVID和流感共享神经系统的副作用,如认知障碍和疲劳. 这两种情况都可能涉及病毒进入大脑和系统性炎症,影响大脑健康.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 神经科学是一个神经科学.
背景情况:
- 由于COVID-19的流行,导致出现了
- 长时间的COVID,
- 具有持续的神经症状的特征.
- 对流感的研究提供了对病毒性呼吸道感染潜在的长期神经系统后果的见解.
研究的目的:
- 审查和强调流感和COVID-19的神经影响中的共同点.
- 探索神经系统后续的共同潜在机制.
- 为了比较神经效应的历史和现代例子.
主要方法:
- 文学评论比较流感和COVID-19的神经影响.
- 专注于潜在的机制:病毒性神经缩和外周炎症.
- 讨论认知障碍,疲劳,抑郁和焦虑.
主要成果:
- 流感和COVID-19共享神经系统的后果,包括认知障碍,疲劳,抑郁和焦虑.
- 常见的潜在机制包括病毒性神经变和失调的外周炎症.
- 加剧的外周炎症导致中枢神经系统功能障碍是关键的共享途径.
结论:
- 流感和COVID-19的神经影响之间的比较对长期COVID研究有价值.
- 了解共享机制可以指导长期COVID神经病理学的未来研究.
- 这些见解可能预示着COVID-19幸存者的长期大脑健康结果.
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