基因组序列和注释的B3真菌菌的Phayeta
Emily Bishop1, Warren Earley1, Alexandra Greco1
1Department of Biology, Coastal Carolina University, Conway, South Carolina, USA.
Microbiology resource announcements
|November 28, 2023
概括
研究人员在南卡罗来纳州的土壤中发现了Mycobacteriophage Phayeta. 它的基因组分析揭示了104个潜在的蛋白质编码基因,有助于了解菌体的多样性和功能.
科学领域:
- 微生物学 微生物学
- 基因组学就是基因组学.
- 病毒学 病毒学
背景情况:
- 菌菌体是感染菌菌体细菌的病毒.
- 土壤环境是各种微生物群落的庇护所,包括菌体.
研究的目的:
- 从南卡罗来纳州的土壤样本中分离和鉴定一种新型菌根菌.
- 为了对隔离的菌体进行基因组注释.
主要方法:
- 使用*Mycobacterium smegmatis*的*丰富培养物*分离菌体.
- 基因组测序和生物信息分析以确定编码蛋白质的基因.
主要成果:
- 菌根菌Phayeta被成功分离出来.
- 菌体拥有68,700个基本对循环 permuted基因组.
- 确定了104个预测的蛋白质编码基因,其中34个具有已知的功能分配.
结论:
- 鉴定了Mycobacteriophage Phayeta的特征,为不断增长的mycobacteriophage基因组数据库作出了贡献.
- 基因组洞察力为未来对这种菌体的功能研究提供了基础.
关键词:
细菌菌体是一种细菌.相关概念视频
Lytic Cycle of Bacteriophages
70.8K
Bacteriophages, also known as phages, are specialized viruses that infect bacteria. A key characteristic of phages is their distinctive “head-tail” morphology. A phage begins the infection process (i.e., lytic cycle) by attaching to the outside of a bacterial cell. Attachment is accomplished via proteins in the phage tail that bind to specific receptor proteins on the outer surface of the bacterium. The tail injects the phage’s DNA genome into the bacterial cytoplasm. In the...
70.8K
Lysogenic Cycle of Bacteriophages
62.2K
In contrast to the lytic cycle, phages infecting bacteria via the lysogenic cycle do not immediately kill their host cell. Instead, they combine their genome with the host genome, allowing the bacteria to replicate the phage DNA along with the bacterial genome. The incorporated copy of the phage genome is called the prophage. Some prophages can re-activate and enter the lytic cycle. This often occurs in response to a perturbation, such as DNA damage, but can also transpire in the absence of...
62.2K
Genome Annotation and Assembly
18.9K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
18.9K


