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Gene Digital Circuits Based on CRISPR-Cas Systems and Anti-CRISPR Proteins
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在细菌中,CRISPR-dCas13a系统用于可编程的小RNA和多基斯特龙mRNA抑制

Sung Cheon Ko1,2, Han Min Woo1,2,3

  • 1Department of Food Science and Biotechnology, Sungkyunkwan University (SKKU), 2066 Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea.

Nucleic acids research
|November 28, 2023
PubMed
概括

研究人员开发了一种CRISPR引导的dCas13a系统,以精确控制细菌小RNA (sRNA). 这种工具使得有针对性的基因抑制成为可能,增强了诸如改善大肠杆菌中利科生产等应用.

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