意大利黑色素瘤的描述性流行病学发生了变化 - - 变得更好
Lauro Bucchi1, Silvia Mancini2, Emanuele Crocetti1
1Romagna Cancer Registry, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) Dino Amadori, Meldola, Forlì-Cesena, Italy.
Italian journal of dermatology and venereology
|November 28, 2023
概括
意大利的黑色素瘤发病率上升,但在年轻人中下降. 针对性疗法和免疫疗法的进步提高了生存率,缩小了性别差距.
科学领域:
- 流行病学 流行病学
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
背景情况:
- 分析了意大利从20世纪90年代到过去十年的黑色素瘤发病率和生存趋势.
- 根据新的流行病学见解,对以前对黑色素瘤控制的努力进行了评估.
研究的目的:
- 总结和评论有关意大利黑色素瘤控制的发现.
- 评估干预措施和新兴疗法对黑色素瘤结局的影响.
主要方法:
- 分析了40个意大利癌症登记处的数据.
- 检查了三十年来发生率,瘤厚度,存活率和活检趋势.
主要成果:
- 黑色素瘤发病率整体上升,但在35岁以下的人群中稳定或下降.
- 在出生在20世纪70年代中期之前的队列中,风险增加,然后下降.
- 自2013年以来,由于新疗法 (分子向疗法,免疫检查点抑制剂),瘤厚度下降,生存率提高,性别生存差距缩小.
- 皮肤活检率因更多的办公室访问而增加,但活检的比例保持不变.
结论:
- 意大利在黑色素瘤控制方面取得了重大进展.
- 在过去的30年里,有效的全民干预措施已经得到实施.
- 目前的策略为未来的黑色素瘤控制工作提供了坚实的基础.
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