婴儿血清25-OH) D水平的监测及其与骨密度和发育的相关性
1Department of Pediatrics, Tianjin Medical University General Hospital, Tianjin, 300052, China. m18322567998@163.com.
Cellular and molecular biology (Noisy-le-Grand, France)
|November 28, 2023
概括
血清中25-氧维生素D (25(OH) D) 水平对于婴儿的骨健康至关重要. 低25OH) D与骨密度降低和骨代谢受损相关,突显了充分维生素D状态的重要性.
科学领域:
- 儿科 儿科 儿科
- 营养科学 营养科学
- 生物化学 生物化学
背景情况:
- 血清25-基维生素D (25(OH) D是维生素D营养状况的关键指标.
- 维生素D (VD) 对于和的吸收至关重要,直接影响骨健康.
- 婴儿骨发育和骨密度是需要调查的关键健康参数.
研究的目的:
- 为了研究血清25(OH) D水平与婴儿骨密度之间的相关性.
- 分析25(OH) D与其他骨代谢标记物的关系,包括,,酸酶 (ALP) 和副甲状腺激素 (PTH).
主要方法:
- 用超声波测量了150名0-3岁的婴儿的骨密度.
- 婴儿被分为正常 (N) 和异常 (ABN) 的骨密度组.
- 血清中25...OH) D,,,ALP和PTH的水平被分析并与骨密度相关联.
主要成果:
- 与N组相比,ABN组表现出明显较低的25-OH-D,和水平,以及较高的ALP和PTH水平 (P<0.05).
- 血清25(OH) D与骨密度有很强的正相关性 (r=0.918,P<0.01).
- 25D水平与和有积极的关联,与ALP和PTH有负面的关联.
结论:
- 血清25(OH) D的升高对于预防婴儿异常骨密度至关重要.
- 保持适当的25-OH-D水平支持健康的骨代谢,并改善婴儿整体骨健康.
- 这项研究强调了监测和确保婴儿维生素D状况足够,以实现最佳骨发育的重要性.
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