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Updated: Jul 9, 2025

An Adipocyte Cell Culture Model to Study the Impact of Protein and Micro-RNA Modulation on Adipocyte Function
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PTPN2 调节新陈代谢流量,影响β细胞对炎症应激的敏感性

Yong Kyung Kim1, Youngjung Rachel Kim2, Kristen L Wells1

  • 1Barbara Davis Center for Diabetes, University of Colorado Denver Anschutz Medical Campus, Aurora, CO.

Diabetes
|November 28, 2023
PubMed
概括

蛋白氨酸酸酶N2 (PTPN2) 在1型糖尿病 (T1D) 中对胰腺β细胞存活至关重要. 在β细胞中删除PTPN2会恶化T1D炎症,导致高血糖和增加死亡率.

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