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Updated: Jul 9, 2025

High Throughput In Vitro Assessment of Latency Reversing Agents on HIV Transcription and Splicing
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Published on: January 22, 2019

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过早转录终结复合体蛋白PCF11和WDR82在潜伏感染细胞中沉默HIV-1表达

Melissa Ait Said1, Fabienne Bejjani1, Ahmed Abdouni1

  • 1Université Paris Cité, Institut Cochin, INSERM, CNRS, Paris F-75014, France.

Proceedings of the National Academy of Sciences of the United States of America
|November 28, 2023
PubMed
概括

分裂和多化因子PCF11和WDR82蛋白质复合体通过控制过早的转录终止,使潜伏感染细胞的HIV-1转录沉默. 击败PCF11或WDR82会重新激活HIV-1的表达.

关键词:
艾滋病病毒-1 艾滋病病毒-1延迟时间 延迟时间转录 转录 是一种转录.

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