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Yeast As a Chassis for Developing Functional Assays to Study Human P53
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对于p53对压力的"数字"反应的分子机制

Jessy Safieh1, Ariel Chazan1, Hanna Saleem1

  • 1Department of Biology, Technion, Technion City, Haifa 2300003, Israel.

Proceedings of the National Academy of Sciences of the United States of America
|November 28, 2023
PubMed
概括

在p53响应元素 (RE) 中的DNA灵活性决定了基因激活时间. 更灵活的RE允许快速,早期的基因表达,在压力后影响细胞命运决策.

关键词:
DNA扭曲灵活性 灵活性基因表达调节的调节在 p53 里,p53 是一个 p53 的代码.蛋白质/DNA相互作用

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