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222nm的紫外线C光在受感染病原体污染的环境中具有很高的消毒光谱,包括SARS-CoV-2
Byeong-Min Song1, Gun-Hee Lee1, Hee-Jeong Han1
1Laboratory for Infectious Disease Prevention, Korea Zoonosis Research Institute, Jeonbuk National University, Iksan, Republic of Korea.
PloS one
|November 28, 2023
概括
222纳米的紫外线有效消毒细菌和病毒,包括SARS-CoV-2变种,在低剂量. 这种波长为环境和个人卫生应用提供了更安全和更强大的解决方案.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 紫外线 (UV) 光是一种已知的消毒剂.
- 与其他UV-C波长相比,UV-C光,特别是222nm波长,具有较高的灭菌效率和更好的安全性.
- 污染控制对于个人卫生和预防疾病传播至关重要.
研究的目的:
- 为了评估222nm紫外线辐射的杀菌和杀菌效果.
- 为了确定在液体和织物矩阵中无活化细菌和病毒所需的UV-C剂量.
- 评估222nm紫外线作为消毒和个人卫生工具的潜力.
主要方法:
- 殖民地形成单元 (CFU) 试验被用来量化可行的细菌细胞.
- 进行了50%组织培养感染剂量 (TCID50) 试验,以进行病毒定位.
- 用222nm紫外线光源对液体和织物环境中的细菌和病毒样本进行了辐射实验.
主要成果:
- 最低剂量为27mJ/cm2的222nm紫外线可达到95%以上的杀菌活性,对抗阴性和阳性细菌.
- 25.1mJ/cm2的剂量显示出>95%的对低致病性禽流感病毒和SARS-CoV-2的杀毒活性.
- 222纳米的紫外线辐射有效地使SARS-CoV-2变种失活,包括Delta和Omicron.
结论:
- 222nm紫外线是一种高效的细菌和病毒消毒剂.
- 222nm紫外线的特定低剂量提供显著的杀菌和杀毒活性.
- 这项技术为环境消毒和增强个人卫生实践提供了一个有希望和更安全的选择.
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