加速度计衍生体力活动与发生心脏骤停之间的关联
Shuangfa Qiu1,2, Zhenhua Xing1,2
1Department of Emergency Medicine, Second Xiangya Hospital, Central South University, No. 139 Mid-Renmin Road, Changsha 410011, China.
概括
定期的体力活动 (PA),特别是中度至强度的活动,显著降低了心脏骤停 (CA) 的风险. 这种保护作用在女性中比男性更为明显.
科学领域:
- 心脏病学 心脏病学
- 流行病学 流行病学
- 运动科学 运动科学
背景情况:
- 心脏骤停 (CA) 是一个严重的健康问题,死亡率很高.
- 以前的研究集中在急性心血管结果上,对客观测量的体力活动 (PA) 和CA风险的调查有限.
- 了解不同强度的PA和CA之间的剂量反应关系对于公共卫生指南至关重要.
研究的目的:
- 检查加速度计测量体力活动 (PA) 强度与心脏骤停 (CA) 风险之间的关系.
- 确定与CA相关的轻度 (LPA),中度 (MPA) 和剧烈体力活动 (VPA) 的剂量反应曲线.
- 调查PA和CA之间的关系中的潜在性别差异.
主要方法:
- 对98,893名英国生物库参与者的前性队列研究.
- 使用手腕加速度计收集的PA数据,测量总体体积,LPA,MPA和VPA.
- 通过诊断代码识别的事件CA;用受限立方线的Cox比例危险模型分析了关联,包括性别差异.
主要成果:
- 在7.31年的中位数随访期间,共记录了282起事故CA.
- 总的PA与CA风险相反相关.
- 随着MPA和VPA的增加,CA风险显著降低,分别达到大约360分钟/周和20分钟/周;LPA没有显示任何关联.
- 与男性相比,在女性中观察到PA和CA风险之间更强的反向关联.
结论:
- 客观测量的PA,特别是中度和强烈的强度,与心脏骤停的风险降低有关.
- 抗AC的PA的保护作用是剂量依赖的,在MPA和VPA的某些值之后,回报率会下降.
- 与男性相比,女性在心脏骤停风险降低方面似乎从PA中获益更多.
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