对脂质度和微泡收缩的控制温度作为微泡尺寸和外特性微调微调的可能机制
Intesar O Zalloum1,2,3, Amin Jafari Sojahrood1,2,3, Ali A Paknahad4,2,3
1Department of Physics, Toronto Metropolitan University, Toronto M5B 2K3, Ontario, Canada.
Langmuir : the ACS journal of surfaces and colloids
|November 28, 2023
概括
研究人员使用微流体技术创建了具有可调节外特性的均微气泡 (MB). 这允许在各种应用中精确控制MB声响应.
科学领域:
- 声学物理学的声学物理学
- 材料科学是一种材料科学.
- 生物医学工程 生物医学工程
背景情况:
- 微泡 (MB) 声响应与共振频率相关,这取决于尺寸和外特性.
- 控制MB大小和外属性对于优化声学应用至关重要.
- 现有的方法缺乏对MB单分散性和外特性的精确控制.
研究的目的:
- 开发一种微流体方法,用于产生具有可调节外特性的单分散微气泡 (MB).
- 为了研究脂质度和初始直径对MB共振频率,外硬度和粘度的影响.
- 为了证明微调MB对超声波应用的声学行为的可行性.
主要方法:
- 通过水相脂质度控制MB收缩,采用了一种新的微流体技术.
- 单分散的MBs产生了不同的初始直径和脂质度 (5.6,10.0,16.0 mg/mL).
- 在收缩后测量了MB共振频率,外刚度和粘度.
主要成果:
- 增加脂质度显著增加了恒定直径的MB共振频率 (180-210%).
- 增加MB最终直径在恒定的脂质度下降了共振频率 (260-300%).
- 由于收缩的影响,MB外的刚性和粘度随着脂质度的增加和最终直径的增加而增加.
结论:
- 微流体方法成功地产生了具有可调节外特性的单分散MB.
- MB的初始直径和脂质度是控制声响应的关键参数.
- 这种方法为先进的声学和超声波应用提供了MBs的精确微调.
相关概念视频
Membrane Fluidity
Cell membranes are composed of phospholipids, proteins, and carbohydrates loosely attached to one another through chemical interactions. Molecules are generally able to move about in the plane of the membrane, giving the membrane its flexible nature called fluidity. Two other features of the membrane contribute to membrane fluidity: the chemical structure of the phospholipids and the presence of cholesterol in the membrane.Fatty acids tails of phospholipids can be either saturated or...
Micelles
Micelle formation is an intricate process that hinges on the properties of amphiphilic or amphipathic molecules and the conditions of the system in which they are found. Amphiphilic molecules, which have both hydrophilic (water-attracting) and hydrophobic (water-repelling) parts, play a critical role in this process.In aqueous environments, these molecules arrange themselves such that their hydrophilic heads are turned towards the water phase, while their hydrophobic tails are oriented away...


