纽芬兰和拉布拉多州基于人口的门诊抗菌素使用:一项回顾性描述性研究
Benjamin Edwards1, Robert Wilson1, Gerald McDonald1
1Faculty of Medicine (Edwards, Wilson, Daley), Memorial University of Newfoundland; Eastern Health (McDonald, Daley), St. John's, NL.
CMAJ open
|November 28, 2023
概括
纽芬兰和拉布拉多的抗菌药物使用率低于国家数据所表明的水平. 药房数据显示,处方率正在下降,并确定了潜在的管理目标.
科学领域:
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
- 流行病学 流行病学
背景情况:
- 纽芬兰和拉布拉多 (NL) 的抗菌药物使用数据可能不反映人口水平的趋势.
- 这项研究旨在利用药房网络数据来描述门诊抗菌素处方.
研究的目的:
- 描述新foundland和拉布拉多的门诊抗菌素使用情况.
- 为了确定抗菌素处方的模式和趋势.
主要方法:
- 对从2017年6月到2021年6月发行的门诊抗菌素处方进行分析.
- 除了亲肠道,局部抗微生物药物,抗病毒药物和抗真菌药物.
- 通过处方和定义的每日剂量 (DDD) 率来描述抗微生物药物的使用.
主要成果:
- 分析了超过150万份处方,每年每千人741份处方.
- 在研究期间,抗菌素的使用显著下降 (处方率-37%,DDD率-36.1%).
- 根据DDD率,阿莫西西林,多西环素和西普罗夫洛克萨是最常被处方的抗菌药物.
结论:
- 在NL的门诊抗菌素使用率低于此前报告的国家估计.
- 抗微生物药物管理的潜在目标包括长时间的处方时间,高处方医生和高使用患者.
- 需要进一步的研究来评估基于诊断的处方适当性.
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