构建基于X射线图像和临床数据的深度学习放射学模型,用于预测和区分急性和慢性骨质疏松性脊椎骨折:一项多中心研究
Jun Zhang1, Liang Xia2, Jun Tang3
1Department of Radiology, Shanghai Tenth People's Hospital, Clinical Medical College of Nanjing Medical University, 301 Middle Yanchang Road, Shanghai, 200072, PR China (J.Z., G.T.); Department of Radiology, Sir RunRun Hospital affiliated to Nanjing Medical University, 109 Longmian Road, Nanjing, Jiangsu, 211002, PR China (J.Z., L.X., W.Z., J.L., Z.L.).
Academic radiology
|November 28, 2023
概括
一种深度学习放射学模型有效地使用X射线图像来区分急性和慢性骨质疏松性脊椎骨折 (OVF). 将这个模型与临床数据结合在名图中,进一步提高了OVFs的诊断性能.
科学领域:
- 放射学 放射学是一门学科.
- 人工智能的人工智能
- 医疗成像医学成像
背景情况:
- 骨质疏松性脊椎骨折 (OVF) 在区分急性和慢性病例时存在诊断挑战.
- 准确的区分对于适当的治疗和患者管理至关重要.
研究的目的:
- 开发和验证一个深度学习放射学 (DLR) 模型,用于使用X射线图像预测和区分急性和慢性OVF.
- 为了评估将DLR与临床数据整合在一起的nomogram的性能.
主要方法:
- 使用ResNet-50的深度转移学习 (DTL) 方法用于942名患者的X射线图像.
- 从DTL和radiomics的特征被融合,并建立了一个后勤回归模型.
- 使用接收器操作特征曲线评估性能,并在多个队伍中验证.
主要成果:
- 基于RadImageNet的DLR模型在区分急性和慢性OVF方面表现出很高的准确性,在训练队列中AUC高达0.979.
- 结合临床数据的深度学习放射学名录 (DLRN) 显示出更好的性能,达到AUC高达0.981.
- 与单独的DLR模型相比,名图提供了更大的临床益处.
结论:
- 与ImageNet模型相比,RadImageNet模型为区分急性和慢性OVF提供了优越的诊断价值.
- 将临床基线特征集成到名图中,可以显著提高OVF的诊断性能.
更多相关视频
相关概念视频
X-ray Imaging
5.5K
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
5.5K
Radiological Investigation I: X-ray and CT
245
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
245
Imaging Studies for Cardiovascular System III: X-Ray
191
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
191


![Quantitative [18F]-Naf-PET-MRI Analysis for the Evaluation of Dynamic Bone Turnover in a Patient with Facetogenic Low Back Pain](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F58491.jpg&w=3840&q=50)