使用非阻塞性通用血管镜检测到的大动脉瘤和心房动之间存在关联
Saki Mizobuchi1, Keisuke Kojima2, Masatsugu Miyagawa1
1Division of Cardiology, Department of Medicine, Nihon University School of Medicine, 30-1 Ohyaguchi-kamicho, Itabashi-ku, Tokyo, 173-8610, Japan.
Journal of thrombosis and thrombolysis
|November 28, 2023
概括
心房动 (AF) 在冠状动脉疾病患者中显著增加了主动脉血栓的风险. 非阻塞性通用血管镜检查 (NOGA) 显示,在AF患者中,这些血栓的患病率较高,这表明AF与大动脉血栓形成之间存在联系.
科学领域:
- 心脏病学 心脏病学
- 血管医学 血管医学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 心房动 (AF) 是已知的中风和全身栓塞的风险因素.
- 大动脉血栓和动脉硬性斑块是栓塞的潜在来源.
- 非阻塞性通用血管学 (NOGA) 可视化大动脉内脏发现,但其在AF患者的效用尚未研究.
研究的目的:
- 用NOGA在患有和没有AF的患者中调查大动脉内脏发现.
- 评估AF与NOGA检测到的大动脉血栓的存在之间的关联.
主要方法:
- 分析了一组连续283名冠状动脉疾病患者的队列,这些患者在2017年至2022年期间接受了大动脉NOGA.
- 患者被分为AF (n=50) 和非AF (n=233) 组.
- NOGA确定了大动脉内脏发现,包括血栓和斑块,并通过统计分析比较了这些组.
主要成果:
- 与非AF组相比,AF组中主动脉瘤的发生率 (92.0%) 显著高于非AF组 (71.6%,p < 0.001).
- 两组之间在强烈黄色或破裂的斑块上没有发现显著差异.
- 多变量分析证实AF作为主动脉瘤的独立预测因子 (OR 3.87,p = 0.016).
结论:
- 通过NOGA检测到的大动脉血栓的存在与冠状动脉疾病患者的心房动有显著的关联.
- 这些发现突出了AF和大动脉血栓形成之间的潜在联系,需要进一步调查它们在栓塞事件中的作用.
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