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Updated: Jun 29, 2026

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在D-银糖诱导的老化小鼠中,IGF2缺乏促进肝脏通过线粒体功能障碍和上调的CEBPB信号传递促进肝脏衰老

Xiaohai Zhou1, Bowen Tan1, Weiwei Gui1

  • 1Department of Endocrinology, the Affiliated Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Molecular medicine (Cambridge, Mass.)
|November 28, 2023
PubMed
概括

胰岛素样生长因子2 (IGF2) 缺乏会通过损害线粒体功能和上调 CEBPB,加速肝脏衰老. 降低IGF2水平促进细胞衰老,这表明IGF2是抗衰老干预的目标.

关键词:
衰老的衰老 衰老的衰老在CEBPBP的基础上,CEBPBPIGF2 IGF2 的意思是什么肝脏 肝脏 肝脏 肝脏线粒体功能障碍 线粒体功能障碍

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