旁观者对纳洛产品的偏好:一个实地实验
Katherine R Marks1,2, Douglas R Oyler3, Justin C Strickland4
1Department of Behavioral Science, College of Medicine, University of Kentucky, Lexington, KY, USA. katie.marks@ky.gov.
Harm reduction journal
|November 29, 2023
概括
旁观者更喜欢更高剂量的纳洛鼻喷雾剂,用于过量逆转. 易于使用和纳洛剂量显著影响产品选择社区分发.
科学领域:
- 公共卫生 公共卫生
- 紧急医疗 紧急医疗
- 药理学 药理学是指药理学的学科.
背景情况:
- 旁观者纳洛的使用对于减少阿片类药物过量死亡至关重要.
- 选择首选的纳洛产品用于社区分发,增加了旁观者携带和管理这些产品的意愿.
- 了解驱动偏好的产品特征对于有效的过量预防策略至关重要.
研究的目的:
- 评估旁观者对三种FDA批准的纳洛产品的偏好.
- 为了确定影响旁观者选择纳洛给药的关键产品特征.
- 为阿片类药物过量逆转剂的社区分发策略提供信息.
主要方法:
- 在肯塔基州博览会上,503名参与者的便利样本接受了纳洛训练.
- 参与者评估了他们是否愿意使用三个纳洛配方:高剂量鼻喷雾,低剂量鼻喷雾和肌内注射.
- 参与者选择了纳洛产品带回家,并评价了影响他们选择的因素.
主要成果:
- 较高剂量的纳洛鼻喷雾是最受欢迎的产品 (44.4%),其次是肌内注射 (30.1%) 和较低剂量的鼻喷雾 (25.5%).
- 使用方便 (9/10),纳洛剂量 (8/10) 和产品熟悉度 (5/10) 是影响产品选择的最重要因素.
- 旁观者表现出很高的意愿管理所有测试的纳洛配方.
结论:
- 对旁观者纳洛的产品偏好受到特定产品特征的影响,例如易于使用和剂量.
- 随着产品的可用性增加,对纳洛配方可接受性的持续评估至关重要.
- 从有实践经验的个体获得反对于成功采用过量逆转剂和拯救生命至关重要.
相关概念视频
Bystander Effect
9.6K
The discussion of bullying highlights the problem of witnesses not intervening to help a victim. This is a common occurrence, as the following well-publicized event demonstrates. In 1964, in Queens, New York, a 19-year-old woman named Kitty Genovese was attacked by a person with a knife near the back entrance to her apartment building and again in the hallway inside her apartment building. When the attack occurred, she screamed for help numerous times and eventually died from her stab wounds.
9.6K
Spare Receptors
3.6K
Some receptors remain unoccupied even when an agonist produces a maximal response. Such empty ones are called spare receptors. In presence of spare receptors the maximum effect of an agonist drug is achieved with fewer than 100% of the receptors being occupied. To determine the presence of spare receptors, scientists often compare the concentration of the drug needed to produce 50% of the maximum effect (EC50) with the concentration of the drug needed to occupy 50% of the receptors (Kd). If the...
3.6K
Blind Procedures
10.6K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
10.6K
The Placebo Effect
6.2K
The placebo effect occurs when people's expectations or beliefs influence or determine their experience in a given situation. In other words, simply expecting something to happen can actually make it happen.
6.2K
Obedience
32.9K
According to obedience research, we may harm others under the forceful pressures of an authority figure (Milgram, 1974). How about if the inappropriate orders were delivered with less force? The increasing interdependence between nurses and physicians compelled Hofling and his colleagues to explore nurses’ reactions to a potentially harmful medical request made by the perceived authority figure, the doctor (Hofling, Brotzman, Dalrymple, Graves, & Pierce, 1966). In this situation,...
32.9K
Blinding
2.5K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
2.5K


