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Updated: Jul 9, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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染色素绝缘调节矩阵金属蛋白酶基因群表达重编程在侵袭性乳腺癌瘤中

Pere Llinàs-Arias1, Miquel Ensenyat-Mendez1, Sandra Íñiguez-Muñoz1

  • 1Cancer Epigenetics Laboratory, Health Research Institute of the Balearic Islands (IdISBa), Palma, 07120, Spain.

Molecular cancer
|November 29, 2023
PubMed
概括

这项研究揭示了MMP8基因附近的绝缘体元素如何调节矩阵金属蛋白酶 (MMP) 基因,影响三阴性乳腺癌 (TNBC) 侵袭. 修改这个元素减少了癌细胞的侵入性,并预测了疾病的进展.

关键词:
在ATAC-seqq中使用.乳腺癌是什么? 乳腺癌是什么在CTCF中,CTCF是指CTCF.染色是一种染色素.基因调节元件是基因调节元件.这就是Hi-C.绝缘体绝缘体是一个绝缘体.这是入侵的入侵.在MMP1中,MMP1是MMP1.在MMP8中,MMP8是MMP8.在RNA-seqqq.这是一个 cis-regulatory 元素.

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