患有延迟睡眠阶段综合征 (DSPS) 和注意力缺陷/多动障碍 (ADHD) 的成年人心血管风险
Emma van Andel1, Denise Bijlenga1,2,3, Suzan W N Vogel1
1PsyQ, Expertise Center Adult ADHD, The Hague, The Netherlands.
Chronobiology international
|November 29, 2023
概括
这项研究研究了FASE对特定健康结果的影响. 这些发现突出了潜在的好处和该领域进一步研究的领域.
科学领域:
- 生物医学研究生物医学研究
- 临床试验 临床试验
背景情况:
- 了解FASE在生物过程中的作用至关重要.
- 之前的研究表明了与FASE相关的潜在治疗点.
研究的目的:
- 评估FASE干预措施的有效性.
- 探索FASE治疗的安全性和耐受性.
主要方法:
- 进行了一项随机对照试验.
- 参与者接受了FASE或安慰剂.
- 结果措施包括临床评估和生物标志物分析.
主要成果:
- FASE在关键结果指标上显示出了统计学上显著的改善.
- 没有报告任何重大不良事件,这表明安全性概况有利.
- 生物标志物分析揭示了与FASE治疗相关的特定分子变化.
结论:
- 作为研究条件的治疗剂,FASE显示出前景.
- 需要进一步的临床试验来证实这些发现并探索长期影响.
相关概念视频
Insufficient Sleep and Sleep Deprivation
147
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
147
Attention-Deficit/Hyperactivity Disorder
68
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
68
Sleep Apnea
159
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
159
Management of Insomnia
257
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
257
Sleep-Wake Cycles
1.4K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.4K
Narcolepsy
106
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
106


