[儿童感染性圣骨炎的临床和成像特征]
1Department of Rheumatology and Immunology, Children's Hospital Capital Institute of Pediatrics, Beijing 100020, China.
Zhonghua er ke za zhi = Chinese journal of pediatrics
|November 29, 2023
概括
儿科传染性圣骨炎通常表现为单边参与和短暂的病史. 关键指标包括白细胞数量升高,C反应蛋白和红细胞沉积率,以及显著的骨破坏.
科学领域:
- 儿科 儿科 儿科
- 类风湿病学 类风湿病学
- 传染性疾病 传染性疾病
背景情况:
- 儿童感染性神经炎是一种罕见的疾病,可以模仿其他儿科类风湿性疾病.
- 区分传染性神经炎和异常性关节炎对于适当的管理和预后至关重要.
研究的目的:
- 总结儿童传染性圣骨炎的临床,放射性特征和预后.
- 为了比较传染性圣炎与涉及圣关节的儿科异常性关节炎.
主要方法:
- 一项病例对照研究,将12名患有传染性神经炎的儿童与28名患有异常性神经炎的儿童进行比较.
- 分析患者的人口统计,临床特征,实验室参数 (WBC,ESR,CRP) 和成像发现 (MRI,CT).
主要成果:
- 与对照组相比,传染性神经炎病例的病期较短,发烧的患病率较高,WBC,ESR和CRP水平明显升高.
- 在成像上,单边的圣关节干扰和骨损伤在传染性圣炎中更为常见.
- 人类白细胞抗原 (HLA) -B27阳性和结性脊柱炎的家族史在传染性圣炎中较少发生,而不是与异形性关节炎相比.
结论:
- 儿科传染性神经炎的特点是急性发作,通常单方面,并与全身炎症标志物相关.
- 炎症标志物 (WBC,CRP,ESR) 的升高以及骨破坏的成像证据是它与异常性关节炎区分的关键特征.
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