在临床环境中,CoaguChek Pro II系统中国际规范化比率结果的可靠性
Evelyn Cortina-de-la-Rosa1, Raúl Izaguirre-Ávila1, Alejandro Ramírez-Hernández1
1Department of Hematology, National Institute of Cardiology Ignacio Chávez, México City, México.
概括
CoaguChek Pro II,CoaguChek XS Plus和cobas t 411系统显示出对测量前列血时间/国际规范化比率 (PT/INR) 的良好一致. 这些发现支持它们在临床环境中的可靠性,用于准确的PT/INR测试.
科学领域:
- 临床化学 临床化学
- 血液学 血液学 血液学
- 诊断技术 诊断技术的使用
背景情况:
- 美国国家心脏病研究所对CoaguChek XS Plus系统进行了经验,用于分析毛细血管血液中的前列血时间/国际正常化比率 (PT/INR).
- 之前的比较涉及到BCS-XP/Thromborel系统.
研究的目的:
- 评估从第三代CoaguChek Pro II系统中获得的PT/INR结果的可靠性和一致性.
- 为了将CoaguChek Pro II系统与CoaguChek XS Plus系统以及cobas t 411分析仪进行静脉和毛细血管血液样本的比较.
主要方法:
- 总共进行了204次静脉和毛细血管PT/INR测量.
- 统计分析包括斯皮尔曼相关性,布兰德-阿尔特曼分析和一致性分析,以比较不同的测试方法.
主要成果:
- 在所有测试系统之间观察到静脉/毛细血管INR的高斯皮尔曼相关系数 (范围从r=0.967到r=0.994).
- 在毛细血管方法 (κ=0.888) 和cobas t 411和CoaguChek系统 (κ=0.696和 κ=0.684) 之间发现了良好的一致性.
结论:
- 对于PT/INR测量,CoaguChek Pro II,CoaguChek XS Plus和cobas t 411系统显示出很好的一致性.
- 这些结果表明这些系统的可靠性临床PT/INR测试使用静脉和毛细血管血液.
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