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Updated: Jun 12, 2026

Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases
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Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases

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对HdxSim的推理,开发和验证,HdxSim是一个临床决策支持工具,用于在状细胞贫血儿童中以模型为基础精确剂量基尿素

Alexandra Power-Hays1,2,3, Min Dong2,4, Nieko Punt5

  • 1Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Clinical pharmacology and therapeutics
|November 29, 2023
PubMed
概括

基于模型的精确剂量 (MIPD) 的基尿素改善了患有状细胞贫血 (SCA) 的儿童的结果. 该HdxSim工具准确地预测了最佳的氧尿素剂量,使治疗在全球范围内更容易获得.

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