超分子水凝用于伤口修复和血液静止
Shaowen Zhuo1, Yongping Liang1, Zhengying Wu1
1State Key Laboratory for Mechanical Behavior of Materials, and Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, China. zhaoxinbio@mail.xjtu.edu.cn.
Materials horizons
|November 29, 2023
概括
这篇评论探讨了用于伤口包裹的超分子水凝,详细介绍了交叉连接方法,网络结构以及血液静止和组织修复等高级功能. 它强调了它们在伤口愈合应用中的潜力和未来方向.
科学领域:
- 生物材料科学 生物材料科学
- 材料化学 材料化学
- 再生医学是一种再生医学.
背景情况:
- 超分子水凝具有独特的网络特性和响应能力,使其成为先进伤口带的有前途产品.
- 现有的文献缺乏专门用于伤口修复和静血的超分子水凝包裹的全面审查.
研究的目的:
- 提供超分子水凝敷料用于伤口修复和血液静止的综合性审查.
- 引入主要的交叉连接方法,网络结构和这些水凝的高级功能.
- 讨论当前的挑战和该领域的未来前景.
主要方法:
- 关于用于伤口应用的超分子水凝的最新文献的综述.
- 超分子水凝网络结构的分类和交联原则.
- 分析材料特性和设计策略,以增强伤口愈合功能.
主要成果:
- 详细的交叉连接策略概述,包括结,静电,疏水,宿主 - 客,以及金属 - 连接物协调.
- 超分子水凝网络架构和形成过程的分类.
- 综述了先进的功能,如抗菌性质,组织粘附,药物输送,抗炎作用,以及促进血管生成和血液静止.
结论:
- 超分子水凝由于其调节性质和多种功能,具有明显的伤口修复和血液静止的潜力.
- 对交叉连接策略,网络设计和功能集成的进一步研究对于优化其临床应用至关重要.
- 本综述旨在指导未来的研究和开发创新的超分子基伤口护理解决方案.
相关概念视频
Phases of Wound Repair
6.0K
Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
6.0K
Introduction to Hemostasis
8.0K
Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized,...
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized,...
8.0K
Inflammatory Response II: Inflammatory Exudate and Tissue Repair
5.0K
The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
5.0K


