改变多发性硬化症的饮食和运动 (MoDEMS):一种随机对照试验,用于多发性硬化症和肥胖症的成年人的行为减肥
Jared M Bruce1,2, Julia S Cozart1,3, Robin P Shook4,5,6
1Department of Biomedical and Health Informatics, School of Medicine, University of Missouri-Kansas City, Kansas City, MO, USA.
Multiple sclerosis (Houndmills, Basingstoke, England)
|November 29, 2023
概括
一个远程医疗减肥计划有效地减少了患有多发性硬化症 (MS) 的人的体重. 这项干预措施改善了MS和肥胖症患者的身体活动,流动性和生活质量.
科学领域:
- 神经学 神经学
- 肥胖问题研究研究
- 行为医学是一种行为医学.
背景情况:
- 肥胖是发展多发性硬化症 (MS) 和加剧MS相关残疾的重要危险因素.
- 对于患有MS (pwMS) 的人来说,行为减肥干预措施的有效性尚未得到充分证实.
研究的目的:
- 评估基于小组的远程医疗减肥干预措施在患有肥胖症的pwMS中实现临床显著减肥的有效性.
主要方法:
- 这是一项随机对照试验,涉及71名pwMS被分配到6个月的远程医疗减肥干预或常规治疗 (TAU).
- 干预的重点是减少卡路里和增加体力活动,以既定的健康建议为指导.
- 评估结果使用人体测量,移动性评估,自我报告问卷和加速度计.
主要成果:
- 干预组的平均体重减轻率为8.6%,而TAU组的平均体重减轻率为0.7% (p < .001).
- 65%的干预参与者达到临床上有意义的体重减轻 (≥5%).
- 干预组的参与者在体力活动水平,生活质量,移动性和减少疲劳性方面表现出显著的改善.
结论:
- 基于小组的远程医疗行为干预是有效的促进临床上显著的减肥pwMS的体重.
- 通过这种干预措施实现的减肥与移动性和生活质量的改善有关,这表明对管理多发性硬化症症状有潜在的益处.
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