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化物GM3通过抑制铁死来保护腹腔大动脉瘤

Fangni Zhang1,2, Kan Li2, Wenhui Zhang2

  • 1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Tianjin Institute of Cardiology, The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), The Second Hospital of Tianjin Medical University, Tianjin Medical University, China (F.Z., D.A.).

Circulation
|November 29, 2023
PubMed
概括

降低的化物GM3 (糖脂) 水平与腹腔大动脉瘤 (AAA) 的进展有关. 在血管光滑肌细胞中,GM3可防止铁,这表明GM3是AAA的潜在治疗点.

关键词:
大动脉动脉瘤,腹部铁症化物肌细胞,光滑肌肉甲状腺脂类

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