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Updated: Jul 9, 2025

Detection of Nitric Oxide and Superoxide Radical Anion by Electron Paramagnetic Resonance Spectroscopy from Cells using Spin Traps
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Detection of Nitric Oxide and Superoxide Radical Anion by Electron Paramagnetic Resonance Spectroscopy from Cells using Spin Traps

Published on: August 18, 2012

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检测蛋白质 - 连接物相互作用与氧化物基础上的偏磁性溶解物.

Anja Penk1, Annemarie Danielsson2, Margrethe Gaardløs2

  • 1Institute for Medical Physics and Biophysics, University of Leipzig, Härtelstr. 16/18, D-04107, Leipzig, Germany.

Chemistry (Weinheim an der Bergstrasse, Germany)
|November 29, 2023
PubMed
概括

核磁共振 (NMR) 谱学使用偏磁放松增强剂 (PREs) 可以绘制蛋白质-连接物静电相互作用. 这种方法揭示了蛋白质周围的静电电位,并确定了连接体结合点.

关键词:
核磁共振光谱法 (NMR) 是一种光谱法.分子动力学分子动力学亚氧化物 亚氧化物蛋白质 - 配体相互作用溶剂对磁放松放松增强剂 溶剂对磁放松增强剂

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Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
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