产前孕产妇皮质醇,压力和焦虑,5岁儿童肥胖:一个嵌套的病例对照研究
Karen Matvienko-Sikar1, Emma Butler2, Linda O' Keeffe1
1School of Public Health, University College Cork, Cork, Ireland.
Journal of reproductive and infant psychology
|November 29, 2023
概括
产前母亲的压力,焦虑,抑郁和第二季度的皮质醇水平与5岁的儿童超重或肥胖没有关联. 这项研究发现,怀孕期间母亲的心理健康与儿童晚期体重状况之间没有联系.
科学领域:
- 生殖健康 生殖健康
- 公共卫生 公共卫生
- 儿科 儿科 儿科
背景情况:
- 儿童肥胖症是一个重要的全球公共卫生问题.
- 产前母亲的心理健康是儿童肥胖发展的潜在因素.
- 这项研究调查了母亲产前心理健康和儿童体重结果之间的联系.
研究的目的:
- 为了检查产前母亲皮质醇,压力,焦虑和抑郁症在第二个三个月之间的关联.
- 确定这些母性因素与5岁儿童超重/肥胖之间的关系.
主要方法:
- 使用SCOPE BASELINE队列进行的嵌套病例控制研究.
- 病例:儿童的BMIz-score>+2SD;对照组:儿童的BMIz-score在5岁时为-0.5到0.5SD.
- 孕期15-20周的母体血清皮质醇和自我报告的心理健康措施;使用条件后勤回归.
主要成果:
- 调整后的模型显示,产前母亲的压力,焦虑,抑郁或皮质醇水平与儿童的BMIz-score之间没有显著的关联.
- 压力,焦虑和抑郁的几率比分分别为1.02,1.03和1.04.
- 皮质醇度显示,儿童BMIz-score的赔率比为0.99.
结论:
- 调查结果不支持在5岁的第二个三个月母体皮质醇,压力,焦虑和儿童超重或肥胖之间存在关联.
- 没有证据表明,胎儿在怀孕早期接触到母亲的心理健康指标会影响后来的儿童体重状况.
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