多目标便DNA测试完成率的差异对于结肠直肠癌查
Jeffrey Dong1, Hyder Said1, Samuel J Miller2
1Department of Medicine, Beth Israel Deaconess Medical Center.
Journal of clinical gastroenterology
|November 29, 2023
概括
患者对结直肠癌查的多目标便DNA测试的坚持率仅为60.4%. 在黑人患者和那些有初级保健医生的患者中观察到较低的坚持,这表明潜在的医疗保健获取差异.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 遗传学 是一个遗传学.
背景情况:
- 美国存在结肠直肠癌 (CRC) 查差异,特别是在种族和社会经济方面.
- 基于便的查测试可能会减少查差距,但对多目标便DNA测试的数据有限.
研究的目的:
- 评估患者对多目标便DNA测试的坚持.
- 确定与遵守该CRC选方法相关的因素.
主要方法:
- 进行了一项单中心回顾性队列研究.
- 使用多变量逻辑回归来识别与测试坚持相关的共变量.
主要成果:
- 总体上,多目标便DNA测试的遵守率为60.4% (481/797名患者).
- 根据子组的依赖程度差异很大,从35.8%到78.1%不等.
- 在亚洲患者和先前进行CRC查的患者中观察到更高的坚持;在黑人患者,居住PCP患者和外展计划中的患者中观察到较低的坚持.
结论:
- 很大一部分患者没有完成推的多目标便DNA测试.
- 在子组之间观察到的坚持差异可能表明潜在的医疗保健准入差异.
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