COVID-19和肌肉骨疼痛:当前知识概述
Matteo Castaldo1, Brian D Ebbesen2,3, César Fernández-DE-Las-Peñas2,4
1School of Medicine, Center for Neuroplasticity and Pain, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark - matteo.castaldo@poliambulatoriofisiocenter.com.
Minerva anestesiologica
|November 29, 2023
概括
后COVID疼痛影响高达60%的幸存者,肌肉骨问题如疲劳和关节疼痛是常见的. 了解复杂的原因和开发针对性治疗这种持续性疼痛至关重要.
科学领域:
- * 传染病和免疫学
- * 风湿病学和肌肉骨医学
背景情况:
- *由SARS-CoV-2引起的2019年冠状病毒病 (COVID-19) 导致了全球广泛的感染.
- * 很大比例的COVID-19幸存者经历了持续的COVID后症状,包括疼痛,持续长达一年.
- *肌肉骨疼痛,表现为疲劳,肌痛和关节痛,是流行COVID后的疾病,影响10-60%的人.
研究的目的:
- *审查COVID后肌肉骨疼痛的临床特征,潜在机制和潜在管理策略.
- *强调需要进一步研究COVID后肌肉骨疼痛的复杂病理生理学.
- *讨论当前的争议和管理这种情况的一般方法.
主要方法:
- *文献综述和现有关于COVID后疼痛研究的综合.
- *分析报告的临床表现和建议的病理生理机制.
- * 对肌肉骨疼痛的当前治疗方法和指导方针的检查.
主要成果:
- *肌肉骨疼痛是COVID后疾病中非常普遍的症状,对幸存者产生重大影响.
- * 驱动COVID后肌肉骨疼痛的确切机制尚未完全理解,免疫,生物,心理,遗传和表观遗传因素的贡献.
- *管理策略没有标准化,一般建议采用多学科和多模式方法.
结论:
- *肌肉骨疼痛是COVID-19的重要和复杂的后果,需要进一步调查.
- *对多因素机制的全面理解对于开发有效的治疗方法至关重要.
- *目前建议采用多学科和多模式治疗方法来管理COVID后的肌肉骨疼痛.
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