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Updated: Jul 9, 2025

Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors
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Published on: June 7, 2018

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免疫微环境的异质性揭示了神经母细胞瘤中不同的亚型:对预后和治疗点的洞察力

Yanlan Yang1, Huamei Li2, Donghui Zheng1

  • 1Department of Hematology and Oncology, Shenzhen Children’s Hospital, Shenzhen, Guangdong, PR China.

Aging
|November 29, 2023
PubMed
概括

我们根据功能性基因表达特征确定了新型神经母细胞瘤 (NB) 亚型,揭示了不同的免疫微环境和预后影响. 这项研究为儿童癌症提供了新的治疗目标和个性化治疗策略.

关键词:
药物反应药物反应神经母细胞瘤的神经母细胞瘤预后 预后 预后小型类型 亚型 类型瘤微环境是一个微环境.

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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