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Updated: Jul 9, 2025

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异常的轴突初始段可塑性和ALS hiPSC运动神经元的内在刺激性

Peter Harley1, Caoimhe Kerins2, Ariana Gatt3

  • 1Centre for Gene Therapy & Regenerative Medicine, Kings College London, London SE1 9RT, UK; Centre for Developmental Neurobiology, Kings College London, London SE1 1UL, UK; UCL Queen Square Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, UCL, London, UK.

Cell reports
|November 29, 2023
PubMed
概括

肌缩侧面硬化症 (ALS) 涉及神经元刺激能力的变化. 早期的ALS运动神经元显示较长的轴突初始段 (AIS) 导致过度兴奋,而后期阶段显示较短的AIS和低兴奋.

关键词:
这就是ALS.C9orf7272 是一个很好的方法.科普:神经科学:神经科学是一门课.在TDP-43中使用.轴突的初始段是轴的初始段.恒温的可塑性 恒温的可塑性人类的iPSC.过度刺激性过度刺激性运动神经元 运动神经元发动机单元的发动机单元.在光学遗传学方面,光学遗传学是指光学遗传学.

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