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Updated: Jun 19, 2026

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蛋白MAE:用于蛋白质表面自我监督学习的蒙面自编码器

Mingzhi Yuan1,2, Ao Shen1,2, Kexue Fu1,2

  • 1Digital Medical Research Center, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.

Bioinformatics (Oxford, England)
|November 29, 2023
PubMed
概括

蛋白MAE是一个自我监督的框架,通过利用未标记的数据来克服标签稀缺性来增强蛋白质表面表示. 这种方法可以提高各种任务的性能,并大大降低计算成本.

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Conservation of Protein Domains Over Different Proteins

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Eukaryotic cells can degrade proteins through several pathways. One of the most important amongst these is the ubiquitin-proteasome pathway. It helps the cell eliminate the misfolded, damaged, or unwarranted cytoplasmic proteins in a highly specific manner.
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Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
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