在败血症中控制温度
Marc Doman1, Michael Thy1,2, Julien Dessajan1
1Medical ICU, Paris Cité University- Bichat University Hospital, Assistance Publique - Hôpitaux de Paris, Paris, France.
Frontiers in medicine
|November 29, 2023
概括
在败血症中控制发烧并不能改善结果. 高热和低热 (低体温) 都与危急病患者的败血症预后恶化有关.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 生理学 生理学 生理学
背景情况:
- 发烧是对感染的适应性反应.
- 败血症的温度调节失调带来了一些挑战.
- 管理高热的目的是防止心跳动和器官损伤等并发症.
研究的目的:
- 评估控制发烧对败血症预后的影响.
- 检查与败血症自发性和治疗性低温相关的结果.
主要方法:
- 对可用的队列和随机对照试验的审查.
- 分析有关败血症发烧管理策略的数据.
- 评估与败血症患者低温相关的结局.
主要成果:
- 在重症患者中控制高热 (>39.5°C) 缺乏改善败血症预后的证据.
- 现有数据不支持积极降低发烧以获得更好的败血症结果.
- 自发性和诱导性低温都与败血症的不良结果相关.
结论:
- 对于改善败血症预后,不建议进行激烈的发烧控制.
- 低温,无论是自发的还是治疗性的,都与败血症的不良结果有关.
- 可能需要进一步的研究来澄清在败血症中最佳的温度管理.
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