影响COVID-19老年高血压住院患者死亡率的因素:一项回顾性研究
Qun Xu1, Fangzhou Li2, Xujiao Chen2,3
1School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, People's Republic of China.
Clinical interventions in aging
|November 29, 2023
概括
患有高血压和COVID-19的老年患者经历了更糟糕的结果,包括严重的损伤和更高的死亡率. 功能障碍是这个脆弱人群中死亡的关键预测因素.
科学领域:
- 老年学是指老年学的学科.
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
背景情况:
- 老年人面临COVID-19严重后果的高风险.
- 高血压是老年人常见的并发症,可能会影响COVID-19的预后.
- 了解影响老年高血压COVID-19患者死亡率的因素对于临床管理至关重要.
研究的目的:
- 调查影响COVID-19老年高血压患者死亡率的因素,特别是功能.
- 为了比较高血压和非高血压的老年COVID-19患者之间的结果.
- 确定该人口中死亡的独立风险因素.
主要方法:
- 对748名老年COVID-19患者 (≥65岁) 的回顾性研究.
- 人口统计数据,实验室值,并发症,治疗方法和临床结果的比较.
- 根据年龄和脆弱性对子组进行分析;针对风险因素进行生存分析.
主要成果:
- 老年高血压COVID-19患者的功能较差 (BUN,UA,Scr较高;eGFR较低),严重程度增加,ICU入院和死亡率增加.
- 非常老年和脆弱的高血压子组表现出更高的风险和急性损伤 (AKI) 的更高发病率.
- 死亡的独立风险因素包括晚年 (≥80),心力衰竭,抗病毒/CCB治疗,机械呼吸,AKI和低EGFR (<60).
结论:
- 患有COVID-19的老年高血压患者面临更严重的损伤,疾病进展和死亡率.
- 功能障碍与老年COVID-19患者的死亡率增加密切相关.
- 研究结果强调监测COVID-19的高血压老年人功能的重要性.
相关概念视频
01:28Factors affecting Blood pressure
3.2K
Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
Physiological Factors:
3.2K
01:26Factors Affecting the Risk of Infection
11.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.8K
01:30Factors Influencing Heart Rate
2.7K
The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
2.7K
01:18Hypertension and Regulation of Blood Pressure
2.1K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
2.1K
01:28Special considerations while measuring blood pressure
725
When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
725
01:17Pathophysiology of Heart Failure
1.6K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.6K