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在先前的部分切除术后,治疗细胞癌的热废除疗法的有效性
Mohamed E Abdelsalam1, Tessa N Hudspeth2, Laura Leonards3
1Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
European urology open science
|November 29, 2023
概括
热移除 (TA) 有效地治疗在部分切除术 (PN) 后同一脏的复发性细胞癌 (RCC). 这种最少的侵入性方法为癌管理提供了低的复发率和并发症率.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 最少侵入性的手术
背景情况:
- 重复部分切除术 (PN) 对于侧瘤复发,会带来手术挑战和增加并发症风险.
- 在初始PN后,确定细胞癌 (RCC) 复发的替代性有效治疗方法至关重要.
研究的目的:
- 评估热除 (TA) 的局部瘤疗效,以治疗之前的PN后侧中RCC.
主要方法:
- 追溯分析66名接受TA治疗的患者在PN后 (2005年1月至2019年12月) 的ipsilateral脏瘤.
- 包括对人口统计,瘤特征,手术细节,并发症,病理和瘤/生存结果的评估.
- 使用Kaplan-Meier方法分析了生存率.
主要成果:
- 在86个病变 (中等大小为1.9厘米) 上进行了74次TA手术;使用了射频废除 (60%) 和冷废除 (14%).
- 低并发症率 (3.7% Clavien-Dindo III级) 和高的活检诊断收益率 (95.5%).
- 局部复发发生在4.6%的病变中;5年总生存率为93.1%,无复发生存率为94.4%.
结论:
- 热除显示出显著的局部瘤疗效,用于治疗在部分切除术后在侧脏中复发的脏瘤.
- 辅助手术是一种可行的和有效的治疗选择,与低复发率和并发症率相关,为重复手术提供了有价值的替代方案.
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