患有非功能性垂体腺瘤的患者的视力敏度:手术后的预后因素和长期结果
Erik Uvelius1, Stig Valdemarsson2, Johan Bengzon1
1Neurosurgery, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, 221 85, Lund, Sweden.
Brain & spine
|November 29, 2023
概括
一半患有非功能性垂体腺瘤 (NFPA) 患者的视力敏度 (VA) 降低,但大多数在手术后得到改善. 瘤高度预测减少VA,但恢复预测因素仍然未知.
科学领域:
- 眼科医生 眼科 眼科
- 神经外科 神经外科
- 内分泌学 在内分泌学.
背景情况:
- 非功能性垂体腺瘤 (NFPA) 可以影响视觉敏度 (VA) 和视野缺陷 (VF).
- 在NFPA管理中,术前VA的研究比VF缺陷少.
研究的目的:
- 分析与减少VA相关的手术前因素,包括腺瘤体积.
- 评估NFPA手术后5年的术后VA改善情况.
主要方法:
- 87名接受NFPA初级手术的患者的回顾性审查.
- 手术前和手术后3个月,1-2年和5年的眼科评估.
- 根据最好的/最糟糕的手术前VA对眼睛的分类.
主要成果:
- 55%的患者在手术前已经减少了VA.
- 77%的减少VA患者表现出改善,54%的患者恢复正常.
- 瘤在部以上的高度是减少VA的最佳放射学预测指标;体积计不是附加的.
- 年龄,形瘤高度和VF缺陷是手术前减少VA的危险因素.
结论:
- 减少VA患者中的一半实现完全康复;所有患者可能会出现一些改善.
- 早期的VA改善 (3个月内) 是常见的;超过2年的改善不太可能.
- 减少VA的频率被低估了,结果有助于患者咨询.
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