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使用基于物理的光学神经网络进行折射率断层扫描.

Delong Yang1, Shaohui Zhang1,2,3, Chuanjian Zheng1

  • 1School of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, China.

Biomedical optics express
|November 29, 2023
PubMed
概括

这项研究引入了一个未经训练的多切片神经网络 (MSNN) 进行折射率 (RI) 断层扫描,提高生物样本的成像效率和清晰度. 这本小说MSNN解决了复杂的散射场景中的挑战,为RI断层扫描提供了一个新的范式.

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Total internal reflection fluorescence microscopy or TIRF is an advanced microscopic technique used to visualize fluorophores in samples close to a solid surface with a higher refractive index, such as a glass coverslip. TIRF only allows fluorophores in proximity to the solid surface to be excited. When light from a medium with a lower refractive index (such as air) hits the glass coverslip at a critical angle, the light undergoes total internal reflection stead of passing through the glass.
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